Secret HIV shelter in immune system revealed

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Baltimore: Researchers have detected a refuge in the immune system using which HIV remains in the human body for years.

 A new study has found that people who suppress HIV viruses for years through antiretroviral therapy can develop HIV in myeloid (a type of white blood cell).

 In the study, conducted with the help of the National Institutes of Health, the researchers used a new reduction method to show that HIV can reactivate in specific myeloids and infect new cells.

According to the results of the study published in the journal Nature Microbiology, myeloid cells play a role in its long-term by making HIV a key but unclear target for efforts to eradicate the virus.

 " This study raises questions about the prevailing narrative that monocytes (a type of white blood cells) that are important for treatment have a very short life span," said study author Rebecca Weinheis from Johns Hopkins University.

 He said that yes, these cells have a short life, but research data suggests that HIV may remain in monocytes in people in whom the virus has been suppressed for years. The fact that HIV can be diagnosed in these cells in the long run suggests that there is something that is keeping the mucus present in the myeloid.

 Antiretroviral treatment is effective in treating HIV because it prevents the virus from infecting new cells and increasing numbers. Nevertheless, HIV can be present in inactivated cells and can make hiv secrets. CD4T cells (a type of white blood cells) are the best studied HIV malignancies. Identifying its receptors is very important for the treatment of HIV because if people stop receiving antiretroviral treatment, inactive HIV can become active again

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